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New enkephalinase inhibitors as probes to differentiate “enkephalinase” and angiotensin-converting-enzyme active sites

✍ Scribed by B.P. Roques; M.C. Fournié-Zaluski; D. Florentin; G. Waksman; A. Sassi; P. Chaillet; H. Collado; J. Costentin

Book ID
118940982
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
276 KB
Volume
31
Category
Article
ISSN
0024-3205

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Dansylated tight-binding inhibitors are effective fluorophoric probes for detecting conformational changes of enzyme active sites. In this study they have been employed to examine the effect of anions on the conformation of angiotensin-converting enzyme. The efficiency of radiationless energy transf