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New efficient extragenic microsatellite markers for hemophilia a carrier state diagnostics

✍ Scribed by V. L. Surin; A. V. Luk’yanenko; Yu. A. Luchinina


Book ID
110199363
Publisher
SP MAIK Nauka/Interperiodica
Year
2007
Tongue
English
Weight
235 KB
Volume
43
Category
Article
ISSN
1022-7954

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In this brief communication we report a new intergenic polymorphism at DXS115 as a marker for detection of heterozygotes in families at risk for hemophilia A. Total genomic DNA was isolated from white blood cells, double digested by KpnI and XbaI and hybridized with EcoRI/SstI fragment of the genomi