New Efficient Access to Thieno[3,2-b]pyridine Derivatives via Regioselective Lithiation of 3-Methylthiopyridine.
โ Scribed by Corinne Comoy; Estelle Banaszak; Yves Fort
- Book ID
- 101990453
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 18 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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๐ SIMILAR VOLUMES
## Abstract magnified image Derivatives of thiophene, thieno[2,3โ__b__]pyridine, thieno[5โฒ,4โฒ:4,5]pyrimido[3,2โ__a__]pyridine and thiepine fused with octyl ring have been synthesized and tested for antimicrobial and antifungal activities. The structure of the newly synthesized compounds have been
Alkylation of 1,2,4-triazine-6-thiones with 4-iodobutyne, followed by oxidation to the sulfoxide and intramolecular cycloaddition (at room temperature), gives 2,3-dihydrothieno[2,3-c]pyridines, which are readily dehydrated with acetic anhydride to thieno[2,3\_c]pyridines. The same series of reactio