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New Domino Silyl Enol Ether Reactions in the Synthesis of a Tetrodecamycin Fragment

✍ Scribed by Jing He; Kirill Tchabanenko; Robert M. Adlington; Andrew R. Cowley; Jack E. Baldwin


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
226 KB
Volume
2006
Category
Article
ISSN
1434-193X

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PM3 study of the domino reaction of nitr
✍ Luis R. Domingo; M. Teresa Picher; Juan AndrΓ©s πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 222 KB πŸ‘ 2 views

The molecular mechanism of the domino reaction of nitroalkenes with silyl enol ethers to give nitroso acetal adducts was characterized using computational procedures at the PM3 semiempirical level. The domino process comprises three consecutive steps: the first and rate-determining step is the nucle