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New Diterpenoid Alkaloids from Aconitum recemulosumFranch.

✍ Scribed by Yong-Hui Ge; Shu-Zhen Mu; Shi-Ying Yang; Yang Lu; Jian-Xin Zhang; Ye Wang; Xiao-Jiang Hao

Publisher
John Wiley and Sons
Year
2009
Tongue
German
Weight
194 KB
Volume
92
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Two new diterpenoid alkaloids, racemulosines A (1) and B (2), were isolated from the roots of Aconitum racemulosum Franch. The structures of the new alkaloids were elucidated by analysis of physical and spectroscopic data, and the structure of 1 was further confirmed by a single‐crystal X‐ray diffraction analysis. Furthermore, compound 1, at 2.25⋅10^−4^ mol/l, showed moderate activity against platelet aggregation induced by PAF (platelet‐activation factor).

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