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New developments in telomere length analysis

✍ Scribed by Duncan M. Baird

Book ID
113614628
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
118 KB
Volume
40
Category
Article
ISSN
0531-5565

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Southern blot analysis of terminal restriction fragments (TRFs) is the standard method for quantitative examination of telomere length distributions. Since TRFs contain a subtelomeric component, central parameters of the TRF distribution n(L) such as the arithmetic mean (M) or the median (Me) cannot