✍ Scribed by Jie Li; Liang Xu; Feng-Peng Wang
No coin nor oath required. For personal study only.
Four new myrsinol diterpenes, proliferins A–D (1–4, resp.) were isolated from the EtOH extracts of the roots of Euphorbia prolifera, along with four known compounds, euphorprolitherin B (5), euphorprolitherin D (6), SPr5 (7), and 14‐desoxo‐3‐O‐propionyl‐5,15‐di‐O‐acetyl‐7‐O‐nicotinoylmyrsinol‐14__β__‐acetate (8). Their structures were established on the basis of spectroscopic methods, including HR‐ESI‐MS, and 1D‐ and 2D‐NMR techniques. The cytotoxicity of compounds 1, 3, and 4 against cancer cells was evaluated, with compound 1 being active against A2780 cancer cells.
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## Abstract Five new diterpene polyesters, **1**–**5**, with jatrophane skeletons were isolated from the fresh whole plants of __Euphorbia serrulata.__ The structure elucidation was performed by means of UV/VIS spectroscopy, HR‐ESI‐MS, and advanced two‐dimensional NMR methods, including ^1^H‐NMR, J