New spectrum of allorecognition pathways
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Shuiping Jiang; Osquel Herrera; Robert I Lechler
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Article
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2004
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Elsevier Science
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English
โ 980 KB
It has long been appreciated that MHC alloantigens can be recognized via two pathways; direct and indirect. The relative contributions of these two pathways to transplant rejection are partially understood. In studies of transplantation tolerance it appears that regulatory T cells (Trs) with indirec