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New compounds: Total synthesis of dl-3a,4,6a-cis-4-(4-carboxybutyl)-hexahydropyrrolo[3,4-d]imidazol-2-one hydrochloride (dl-azabiotin hydrochloride)

✍ Scribed by Henry C. Wormser; Hanley N. Abramson


Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
346 KB
Volume
66
Category
Article
ISSN
0022-3549

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Regioselective Synthesis of the 5,6-Dihy
✍ Gani Koza; Emrah Karahan; Metin Balci πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 German βš– 173 KB

## Abstract We hereby report the first preparation of the 5,6‐dihydro‐4__H__‐furo[2,3‐__c__]pyrrol‐4‐one (**3**) and its derivatives starting from methyl 3‐(methoxycarbonyl)furan‐2‐acetate (**8**). The ester functionality connected to the methylene group was regiospecifically converted to the desir