New compounds: Synthesis of alkyl esters of D,L-dopa
โ Scribed by Chii Ming Lai; William D. Mason
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 177 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Isomerization was performed by refluxing solutions of ( 3 j -( 7 ) (5mmol) in 2.0M (12.51111) ethereal zinc iodide solution for 2-4 h. The isomerizations can also be carried out on a preparative scale:
Previous work from this laboratory has shown that the direct fluorination of 3, 4-dihydroxy-phenyl-lalanine (l-DOPA) in anhydrous HF (aHF) or BF 3 /HF with F 2 is an efficient method for the synthesis of 6-fluoro-l-DOPA. Since then, 18 F-labeled 6-fluoro-l-DOPA ([ 18 F]6-fluoro-l-DOPA) has been used
## DOPA-Containing Polypeptides. I. Improved Synthesis o f High-Molecular-Weight Poly( L-DOPA) and Water-Soluble Copolypep tides Despite considerable interest in the pharmacological properties of L-DOPA (3,4-dihydroxy-1,-phenylalanine), the synthesis of polypeptides containing the optically active