New building blocks for peptide and depsipeptide synthesis: hexafluoroacetone protected l-homoisoserine and d,l-homoisocysteine derivatives
✍ Scribed by Gábor Radics; Raul Pires; Beate Koksch; Salah M El-Kousy; Klaus Burger
- Book ID
- 104252794
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 251 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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N-Acetylated threonine derivatives, having tert-butyl or benzyl-based side-chain protection, form isolable 5(4H)-oxazolones on treatment with N-ethyl-N'-3-dimetlaylaminopropyl carbodiimide. N-chloroacetylated threonine derivatives, on the other hand, do not form oxazolones so readily. The N-acetylat
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