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New arahypins isolated from fungal-challenged peanut seeds and their glucose uptake-stimulatory activity in 3T3-L1 adipocytes

โœ Scribed by Liu, Zhongwei; Wu, Jien; Huang, Dejian


Book ID
118253666
Publisher
Elsevier
Year
2013
Tongue
English
Weight
305 KB
Volume
6
Category
Article
ISSN
1874-3900

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Among nine flavonols (1-9) obtained from Sophorae Flos, we first isolated compounds 4, 5, 8, and 9. These isolates (1-9) were evaluated for the phosphorylation of AMPK and ACC. Administered at 10 lM, 9 possessed high potent activity. Compound 9 displayed a dose-dependent stimulation of glucose uptak