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New approach to Strychnos alkaloids. Stereocontrolled total synthesis of (.+-.)-dehydrotubifoline

✍ Scribed by Fevig, John M.; Marquis, Robert W.; Overman, Larry E.


Book ID
111858622
Publisher
American Chemical Society
Year
1991
Tongue
English
Weight
270 KB
Volume
113
Category
Article
ISSN
0002-7863

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An efficient, stereocontrolled synthesis of the tetracyclic bases 1 and 2 by cyclization of the regioiscmeric cyanopiperidines 4 and 5, prepared from the ccxmcn c&-3-ethyl-4-(2-indolylmethyl)piperidine intermediate 3, is reported.