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New Antioxidant Phenolic Glucosides from Viburnum dilatatum

✍ Scribed by Bin Wu; Saiwei Wu; Haibin Qu; Yiyu Cheng

Publisher
John Wiley and Sons
Year
2008
Tongue
German
Weight
199 KB
Volume
91
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Chemical investigation of the fruits of Viburnum dilatatum Thunb. resulted in the isolation and characterization of four new phenolic glycosides, jiamiziosides A–D (1–4), together with five known compounds. Their structures were established by spectroscopic means and by comparison with the literature values. The antioxidant activities of the new isolates were determined against 2,2‐diphenyl‐1‐picrylhydrazyl (=2,2‐diphenyl‐1‐(2,4,6‐trinitrophenyl)hydrazinyl; DPPH) and superoxide radicals. Among the compounds tested, jiamizioside C (3) possesses the most potent inhibitory scavenging effect on DPPH and superoxide radicals with IC~50~ values of 16.8 and 17.8 μM, respectively.

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