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New Antifungal Terpenoid Glycosides from Alibertia edulis (Rubiaceae)

✍ Scribed by Viviane Cândida da Silva; Maria José Soares Mendes Giannini; Virginia Carbone; Sonia Piacente; Cosimo Pizza; Vanderlan da Silva Bolzani; Márcia Nasser Lopes

Publisher
John Wiley and Sons
Year
2008
Tongue
German
Weight
196 KB
Volume
91
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Phytochemical investigation from the stems of Alibertia edulis led to the isolation and identification of a new iridoid 6__β__‐hydroxy‐7‐epigardoside methyl ester (1) and a new saponin 3__β__‐O‐[α‐L‐rhamnopyranosyl‐(1→2)‐O‐β‐D‐glucopyranosyl‐(1→2)‐O‐β‐D‐glucopyranosyl]‐28‐__O‐β‐__D‐glucopyranoside pomolate (2), along with three known compounds, shanzhiside methyl ester (3), ixoside (4), and 3,4,5‐trimethoxyphenyl 1‐O‐β‐D‐apiofuranosyl‐(1→6)‐O‐β‐D‐glucopyranoside (5). The structures of 1 and 2 were established on the basis of their spectroscopic data. Iridoid 1 and saponin 2 exhibited moderate inhibitory activities against Candida albicans and C. krusei in a dilution assay.

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.