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New anticoagulants: pharmacology and clinical studies

✍ Scribed by Charles Marc Samama

Publisher: Springer Vienna
Year: 2011
Tongue: German
Weight: 84 KB
Volume: 161
Category: Article
ISSN: 0043-5341
DOI: 10.1007/s10354-011-0875-9

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## Abstract Clinically used anticoagulants are inhibitors of enzymes involved in the coagulation pathway, primarily thrombin and factor Xa. These agents can be either direct or indirect inhibitors of clotting enzymes. Heparin‐based anticoagulants are indirect inhibitors that enhance the proteinase