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New Antibacterial Diterpenes from Pseudopterogorgia elisabethae

✍ Scribed by Athar Ata; Hla Y. Win; David Holt; Paul Holloway; Edward P. Segstro; Gamini S. Jayatilake

Publisher
John Wiley and Sons
Year
2004
Tongue
German
Weight
131 KB
Volume
87
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

From the MeOH extract of Pseudopterogorgia elisabethae, collected from the Bahamas, four new diterpenes, elisabethin E (1), elisabethin F (2), pseudopterosin P (3), and pseudopterosin Q (4), were isolated and their structures established with the aid of extensive spectroscopic studies. Compounds 3 and 4 showed antibacterial activity selectively against the __Gram‐__positive bacteria Streptococcus pyogenes, Staphylococcus aureus, and Enterococcus faecalis.

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