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New annulation processes for fused and spiro rings based on the chemistry of benzothiazoles

✍ Scribed by E.J. Corey; Dale L. Boger


Publisher
Elsevier Science
Year
1978
Tongue
French
Weight
342 KB
Volume
19
Category
Article
ISSN
0040-4039

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A novel, one-step annulation process for
✍ E.J Corey; Wei-guo Su πŸ“‚ Article πŸ“… 1987 πŸ› Elsevier Science 🌐 French βš– 214 KB

The reaction of the dilithio derivative of dimethyl cis-4-cyclohexen-1,2-dicarboxylate with 3substituted propiolic acid phenyl esters proceeds via an unusual mechanistic path to generate fused bicyclic 2cyclopentenones in a single step. The first total synthesis of a member of the gingkolide family