A novel, one-step annulation process for
β
E.J Corey; Wei-guo Su
π
Article
π
1987
π
Elsevier Science
π
French
β 214 KB
The reaction of the dilithio derivative of dimethyl cis-4-cyclohexen-1,2-dicarboxylate with 3substituted propiolic acid phenyl esters proceeds via an unusual mechanistic path to generate fused bicyclic 2cyclopentenones in a single step. The first total synthesis of a member of the gingkolide family