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New Amides of 5-Acylamino-3-Methyl-4-Isothiazolecarboxylic Acid and their Immunotropic Activity

✍ Scribed by Urszula Lipnicka; Andrzej Regiec; Emil Sułkowski; Michał Zimecki


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
100 KB
Volume
338
Category
Article
ISSN
0365-6233

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A series of 5-aminomethinimino-3-methyl-4-isoxazolecarboxylic acid phenylamides 4 has been prepared by condensation of 5amino-3-methyl-4-isoxazolecarboxylic acid phenylamides 1 with trichloroacetic aldehyde. Alcoholysis of trichloro derivatives 2 gave 5-alkoxymethine derivatives 3 which, on reaction