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New alkaloids of the lamellarin class from the marine ascidian Didemnum chartaceum (Sluiter, 1909)

✍ Scribed by Lindquist, Niels; Fenical, William; Van Duyne, Gregory D.; Clardy, Jon


Book ID
115470602
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
666 KB
Volume
53
Category
Article
ISSN
0022-3263

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Synthesis of didemnolines A-D, N9-substi
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Didenmolines A-D (1-4) were synthesized and their suuctures were confirmed through comparisons of data for the synthetic material with those obtained for natural 1-4. The synthesis of didenmolines A (1) and C (3) involved the coupling of 1-[(benzyloxy)methyl]-4-chloromethyl-5-(thiomethyl)imidazole (