✦ LIBER ✦
New Acyclic 12-Hydroxygeranylgeraniol-Derived Diterpenoids from the Seeds of Carpesium triste
✍ Scribed by Xue Gao; Zhan-Xin Zhang; Zhong-Jian Jia
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- German
- Weight
- 186 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
Five new acyclic 12‐hydroxygeranylgeraniol‐derived diterpenoids, i.e., 1–5, were isolated from the seeds of Carpesium triste. The structures including the absolute configurations of the new compounds were elucidated by spectroscopic methods. All the compounds, except for 2, were evaluated for their in vitro cytotoxic activity against cultured SMMC‐7721 (human hepatoma), HL‐60 (human promyelocytic leukemia), and L02 (human hepatocyte) cells.