## Abstract 1,4‐Disubstituted thiosemicarbazides **1b–f** reacted with ethenetetracarbonitrile (**5**) in di‐ methylformamide with formation of 2‐substituted 5‐phenyl‐1,3,4‐thiadiazoles **2a–f** and 2‐substituted 5‐phenyl‐1,3,4‐oxadiazoles **4a–f**. Upon addition of **5** to **1c–e** in chlorobenze
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New Access to Pyrazole, Oxa(thia)diazole and Oxadiazine Derivatives.
✍ Scribed by Alaa A. Hassan; Kamal M. El-Shaieb; Raafat M. Shaker; Dietrich Doepp
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 22 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Treatment of 3‐(3‐methylbenzofuran‐2‐yl)‐3‐oxopropanenitrile (**1**) with phenyl isothiocyanate afforded the thioacetanilide derivative **3**, which when reacted with α‐haloketones, α‐halodiketones, and hydrazonoyl chlorides gives thiophene, 1,3‐oxathiole, and 1,3,4‐thiadiazole derivati