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New 5-substituted 1-alkyl-2-nitroimidazoles

✍ Scribed by Cavalleri, Bruno; Ballotta, Roberto; Arioli, Vittorio; Lancini, Giancarlo


Book ID
120364304
Publisher
American Chemical Society
Year
1973
Tongue
English
Weight
491 KB
Volume
16
Category
Article
ISSN
0022-2623

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A new synthetic approach, involving an S RN 1 reaction of the anion of 1-methyl-4-phenylsulfonyl-methyl-5-nitro-1Himidazole with 2,2-dinitropropane and a radical anion or a concerted radical reductive elimination of sulfonyl and nitro groups affords an original 5-nitroimidazole bearing a trisubstitu