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Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase

✍ Scribed by Talukdar, Saswata; Oh, Da Young; Bandyopadhyay, Gautam; Li, Dongmei; Xu, Jianfeng; McNelis, Joanne; Lu, Min; Li, Pingping; Yan, Qingyun; Zhu, Yimin; Ofrecio, Jachelle; Lin, Michael; Brenner, Martin B; Olefsky, Jerrold M

Book ID
111980863
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
835 KB
Volume
18
Category
Article
ISSN
1078-8956

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Consumption of a diet high in barley b-glucan (BG) has been shown to prevent insulin resistance. To investigate the mechanism for the effects of barley BG, three groups of male 7-wk-old C57BL/6J mice were fed high-fat diets containing 0, 2, or 4% of barley BG for 12 wk. The 2% BG and 4% BG groups ha