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Neutrophilic panniculitis with myelodysplastic syndromes presenting as pustulosis: Case report and review of the literature

✍ Scribed by Hsiang-Cheng Chen; Woei-Yau Kao; Deh-Ming Chang; Hong-Wei Gao; Wei-Yu Lai; Jenn-Haung Lai

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
173 KB
Volume
76
Category
Article
ISSN
0361-8609

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✦ Synopsis

Abstract

Neutrophilic panniculitis associated with myelodysplastic syndromes is rare. We report a 59‐year‐old patient who initially was diagnosed with myelodysplastic syndrome (MDS) and developed a sudden onset of widespread pustulosis and erythematous indurated papules. Examination of skin biopsies of a papule lesion showed dense neutrophilic infiltration limited to the subcutaneous tissue. The pustules and papules disappeared completely after treatment with systemic corticosteroids. To our knowledge, only one patient was identified by MEDLINE search of the English‐language literature. Am. J. Hematol. 76:61–65, 2004. © 2004 Wiley‐Liss, Inc.

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