𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Neutrophil-lymphocyte ratio as a prognostic factor in colorectal cancer

✍ Scribed by S.R. Walsh; E.J. Cook; F. Goulder; T.A. Justin; N.J. Keeling

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
72 KB
Volume
91
Category
Article
ISSN
0022-4790

No coin nor oath required. For personal study only.

✦ Synopsis

Background and Objectives: Simple methods to identify colorectal cancer patients at risk of recurrence are needed. This study aimed to determine if neutrophil-tolymphocyte ratio (NLR) predicts survival in colorectal cancer patients. Methods: Two-hundred thirty patients diagnosed with colorectal cancer over a twoyear period were identified from a prospectively maintained colorectal cancer database. NLR was calculated from pre-operative full blood counts. In the case of patients who did not undergo surgery, the full blood count from their out-patient visit was used. Known prognostic factors were recorded. Overall and cancer-specific survival were calculated. Results: Pre-operative NLR greater than 5 correlated with overall and cancer-specific survival in univariate analyses. NLR was not independent of Dukes stage. Conclusions: Pre-operative NLR may represent a simple method of identifying colorectal cancer patients with a poor prognosis pre-operatively.

πŸ“œ SIMILAR VOLUMES

Evaluations of interferon-Ξ³/interleukin-
Evaluations of interferon-Ξ³/interleukin-4 ratio and neutrophil/lymphocyte ratio as prognostic indicators in gastric cancer patients
✍ Hideyuki Ubukata; Gyou Motohashi; Takanobu Tabuchi; Hiroyuki Nagata; Satoru Koni πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 318 KB

## Abstract ## Background and Objectives Th2‐dominant immunity and high neutrophil/lymphocyte ratios (NLRs) have been reported to reflect tumor progression, and so we examined whether the Th1/Th2 ratio and NLR can act as prognostic indicators or not. ## Methods Peripheral blood samples were take

Age as a prognostic factor in breast can
Age as a prognostic factor in breast cancer
✍ Herman HΓΈst; Eiliv Lund πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 451 KB πŸ‘ 2 views

The influence of age on survival was studied in an unselected series of 31,594 females with breast cancer reported to The Cancer Registry of Norway during 1955-1980. The prognosis was best in patients aged 35 to 49 years, and poorest in the older (275 years) and the younger patients (534 years). The

Age as a prognostic factor in breast can
Age as a prognostic factor in breast cancer
✍ Hans-Olov Adami; Birgitta Malker; Olav Meirik; Ingemar Persson; Leif Bergkvist; πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 English βš– 451 KB πŸ‘ 2 views

Long-term survival was evaluated in a total of 12,319 women with first breast cancer, comprising 94.9% of virtually all women with first breast cancers diagnosed in Sweden in 1959 through 1963. After correction for the expected mortality, it was found that age at diagnosis was an important predictor