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Neutrophil function screenlng in patients with chronic granulomatous disease by a flow cytometric method

✍ Scribed by C. L. Epling; D. P. Stites; T. M. McHugh; H. O. Chong; L. L. Blackwood; D. W. Wara


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
606 KB
Volume
13
Category
Article
ISSN
0196-4763

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A rare subgroup (approx. 5%) of all chronic granulomatous disease (CGD) patients suffers from mutations in the gene encoding the small p22-phox subunit of the flavocytochrome b558 heterodimer, the terminal redox component of the phagocyte NADPH oxidase. A male CGD patient with neutrophil granulocyte