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Neutralizing monoclonal antibodies define two different functional sites in human interleukin-4

✍ Scribed by Petra REUSCH; Stefan ARNOLD; Christoph HEUSSER; Kathrin WAGNER; Beverly WESTON; Walter SEBALD


Book ID
115130836
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
992 KB
Volume
222
Category
Article
ISSN
1432-1327

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A panel of three hybridomas has been isolated each of which secretes a single species of monoclonal antibody (MoAb) directed against the KS1/4 tumor-associated antigen originally described by Varki et al. (Cancer Res 44: 681, 1984). These MoAbs were designated L1-(IgG2b), L2-(IgG1), and L4-(IgG2a)KS