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Neutralizing antibodies to human and simian adenoviruses in humans and New-World monkeys

✍ Scribed by Jonatan Ersching; Malva I.M. Hernandez; Fabrizzio S. Cezarotto; Jovino D.S. Ferreira; Amely B. Martins; William M. Switzer; Zhiquan Xiang; Hildegund C.J. Ertl; Carlos R. Zanetti; Aguinaldo R. Pinto

Book ID
113948154
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
526 KB
Volume
407
Category
Article
ISSN
0042-6822

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## Abstract ## Background Oncolytic adenoviruses are an attractive strategy for treating cancers resistant to conventional treatments. However, their systemic utility could be limited as a result of the high prevalence of pre‐existing immunity towards the vector. Furthermore, neutralizing antibodi