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Neutralization of Circulating Vascular Endothelial Growth Factor (VEGF) by Anti-VEGF Antibodies and Soluble VEGF Receptor 1 (sFlt-1) Induces Proteinuria

✍ Scribed by Sugimoto, Hikaru (author);Hamanog, Yuki (author);Charytan, David (author);Cosgrove, Dominic (author);Kieran, Mark (author);Sudhakar, Akulapalli (author);Kalluri, Raghu (author)


Book ID
125508244
Publisher
The American Society for Biochemistry and Molecular Biology
Year
2003
Tongue
English
Weight
808 KB
Volume
278
Category
Article
ISSN
0021-9258

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## Abstract Angiogenesis, the formation of new blood vessels, is controlled by a balance between positive and negative endothelial regulatory factors. Soluble vascular endothelial growth factor receptor‐1 (sVEGFR1), a naturally occurring soluble form of VEGFR1, is a negative counterpart of the vasc