β Scribed by Albert Jan De Groot; Jan Jager; Jan B.F.N. Engberts
No coin nor oath required. For personal study only.
Rates and thermodynamic activation parameters have been determined for the watercatalyzed hydrolysis of l-benzoyl-3-phenyl-l,2,4-triazole (1) in aqueous solutions containing l:l copolymers of maleic acid with ethyl vinyl ether (MAc-EVE), ethyl vinyl ether/n-butyl vinyl ether (l:l) (MAc-EVE-nBVE), n-butyl vinyl ether (MAc-n BVE), and n-hexyl vinyl ether (MAc-nHVE). Substantial retardations are found in the presence of MAc-nBVE and MAc-nHVE and a modest inhibition in solutions containing MAc-EVE-n BVE but MAc-EVE hardly affects the hydrolysis of 1. The inhibitions are interpreted in terms of hydrophobic binding of 1 to the compact conformation of the unionized copolymer and subsequent hydrolysis at relatively "dry" binding sites in the hydrophobic microdomains. An increase of the degree of ionization of MAc-nBVE and MAc-nHVE ultimately leads to a conformational transition to an extended coil and a concomitant decrease of the retardation.
π SIMILAR VOLUMES
A~tract:~~~~~rats~~fartheti~enactiongiveacwilinearplotvrr~tertiaryamine concentration, according to the quatim kA = (& + Kt~LZ[TEAl)/(l + KtmA]). This shows the occure.nce of two different reaction pathways; the one, Wepndent of ml and the other, dependaN on ITEA]. which involves a fast convcxsion o