Chemistry of glycosphingolipids in Fabry
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C.C. Sweeley; P.D. Snyder Jr.; C.E. Griffin
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Article
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1970
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Elsevier Science
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English
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Two glycosphingolipids that accumulate in patients with Fabry's disease were isolated from abnormal kidney by gradient elution chromatography on silicic acid. A combination of periodate oxidation, mild acid hydrolysis, permethylation, and gas chromatographic studies of the sugar moieties established