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Neurotrophin 4 enhances in vitro follicular assembly in human fetal ovaries

โœ Scribed by Jacob Farhi; Benjamin Fisch; Roni Garor; Yoav Peled; Haim Pinkas; Ronit Abir


Book ID
116476854
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
974 KB
Volume
95
Category
Article
ISSN
1556-5653

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The recombinant form of the extracellular domain of the IL-4 receptor (sIL-4R) is a potential candidate to neutralize IL-4; however, murine sIL-4R displayed both antagonistic and agonistic activity in vivo. Here we show that human recombinant sIL-4R induced the formation of complexed IL-4 in superna