Neurotransmitter and Dementia

✍ Scribed by Dr. T. Goto, F. Kuzuya, H. Endo, T. Tajima, H. Ikari (auth.), Prof. Dr. C. G. Gottfries, Prof. Dr. S. Nakamura (eds.)

Publisher: Springer-Verlag Wien
Year: 1990
Tongue: English
Leaves: 86
Series: Journal of Neural Transmission 30
Edition: 1
Category: Library

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✦ Synopsis

Neurotransmitter changes taking place in the brain of patients with dementia disorders, mainly Alzheimer type dementia, are reported. Their role in the pathogenesis of Alzheimer's disease is discussed; and the neurochemical changes are considered as a base for formulating treatment strategies. By studying markers in the cerebrospinal fluid, diagnostic methods may be achieved that will aid in diagnosing subgroups of dememtia.

✦ Table of Contents

Front Matter....Pages i-vii
Some effects of CNS cholinergic neurons on memory....Pages 1-11
Subcellular distribution of acetylcholinesterase in Alzheimer’s disease: abnormal localization and solubilization....Pages 13-23
Changes of acetylcholine and choline concentrations in cerebrospinal fluids of normal subjects and patients with dementia of Alzheimer-type....Pages 25-32
Disturbance of the 5-hydroxytryptamine metabolism in brains from patients with Alzheimer’s dementia....Pages 33-43
CSF β -endorphin, HVA and 5-HIAA of dementia of the Alzheimer type and Binswanger’s disease in the elderly....Pages 45-55
Neuropeptide levels in Alzheimer’s disease and dementia with frontotemporal degeneration....Pages 57-67
Changes in signal transduction in Alzheimer’s disease....Pages 69-78
Back Matter....Pages 79-87

✦ Subjects

Neurosciences; Pharmacology/Toxicology; Psychiatry; Analytical Chemistry

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