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Neurotoxins and Their Binding Areas on Voltage-Gated Sodium Channels

✍ Scribed by Stevens, Marijke; Peigneur, Steve; Tytgat, Jan

Book ID
119970448
Publisher
Frontiers
Year
2011
Tongue
English
Weight
710 KB
Volume
2
Category
Article
ISSN
1663-9812

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This study was undertaken to assess the binding properties of BmK AS on both mammal and insect excitable cell membranes. It was found that BmK AS bound specifically to a single class of non-interacting binding sites on both rat brain and cockroach nerve cord synaptosomes with high affinity (K d Ο­ 1.