✦ LIBER ✦
Neurotoxicity of organophosphorus pesticides: predictions can be based on in vitro studies with hen and human enzymes
✍ Scribed by Marcello Lotti; Martin Keith Johnson
- Publisher
- Springer-Verlag
- Year
- 1978
- Tongue
- English
- Weight
- 405 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0340-5761
No coin nor oath required. For personal study only.
✦ Synopsis
The comparative inhibitory power of organophosphorus esters in vitro against hen brain acetylcholinesterase and neurotoxic esterase correlates with their comparative effects (death or delayed neuropathy) in vivo, Further comparisons of the in vitro effects seen with hen and human enzymes facilitates extrapolations to the human in vivo situation.