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Neurotoxic lesions of the paraventriculo-spinal projection block the nocturnal rise in pineal melatonin synthesis in the Syrian hamster

โœ Scribed by Hastings, M.H.; Herbert, J.


Book ID
122455506
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
511 KB
Volume
69
Category
Article
ISSN
0304-3940

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The nocturnal pattern of Syrian hamster pineal melatonin synthesis is characterized by a 6-8 h lag period, followed by a late-night, short-duration peak in both N-acetyltransferase (NAT) activity and melatonin content. Administration of cycloheximide (20 mgkg body weight) given either at the time of