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Neurotoxic effects of phenytoin administered to newborn mice on granule cells and Purkinje cells in the developing cerebellum

โœ Scribed by H. Ohmori; T. Hatta; K. Yamashita; M. Yasuda; K. Mikoshiba


Book ID
114279785
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
130 KB
Volume
18
Category
Article
ISSN
0892-0362

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We evaluated the relationship among proliferation, death and migration of granule cells in lobules VI-VIII of vermis, in comparison with lobule III, during cerebellar development. To this aim, a single injection of cisplatin, i.e., a cytostatic agent that is known to induce death of proliferating gr