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Neurotoxic effect of 1-methyl-4-phenylpyridinium ion on dopaminergic neurons of the retina of goldfish

✍ Scribed by Villani, L.; Poli, A.; Bissoli, R.; Barnabei, O.


Book ID
122976495
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
677 KB
Volume
86
Category
Article
ISSN
0304-3940

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We have studied the effect of a semichronic and acute treatment of phenobarbital on in vivo 1-methyl-4-phenylpyridinium ion- (MPP+)-induced neurotoxicity. A group of rats were intraperitoneally injected for 12 days with phenobarbital (80 mg/Kg of body weight, semichronic treatment) in order to induc