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Neurotensin modulates autoreceptor mediated dopamine effects on midbrain dopamine cell activity

โœ Scribed by Wei-Xing Shi; Benjamin S. Bunney

Book ID
115801368
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
708 KB
Volume
543
Category
Article
ISSN
0006-8993

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Effects of neurotensin on midbrain dopam
Effects of neurotensin on midbrain dopamine neurons: Are they mediated by formation of a neurotensinโ€”dopamine complex?
โœ Dr. Wei-Xing Shi; Dr. Benjamin S. Bunney ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 766 KB

## Abstract The effects of neurotensin on midbrain dopamine neuron activity were studied in brain slices using singleโ€unit recording techniques. At low concentrations (0.2โ€“10 nM), neurotensin attenuated dopamineโ€induced inhibition without a significant effect on the basal firing rate. At higher con