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Neurotensin and nonpeptide neurotensin receptor antagonist control human colon cancer cell growth in cell culture and in cells xenografted into nude mice

โœ Scribed by Maoret, J.J.; Anini, Y.; Rouyer-Fessard, C.; Gully, D.; Laburthe, M.


Book ID
122998117
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
169 KB
Volume
114
Category
Article
ISSN
0016-5085

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## Abstract Neurotensin (NT) is a highly expressed gastrointestinal (GI) neuropeptide, which modulates GI motility, secretion and cell growth as well as intestinal inflammation. Since EGF receptor is highly expressed in human colon cancer cells, we sought to examine whether NT stimulation contribut