A 20-month-old boy had an &week history of vomiting, lethargy, generalized muscle weakness, and seizures. There was no history or clinical signs of an underlying systemic disease or an immunodeficiency. Cerebrospinal fluid (CSF) had 99 nucleated cellsku mm, malignant cells, high protein and normal g
Neuroradiological findings in a child with primary leptomeningeal melanoma
β Scribed by O. Flodmark; C. R. Fitz; D. C. Harwood-Nash; S. H. Chuang
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 423 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0028-3940
No coin nor oath required. For personal study only.
β¦ Synopsis
A case of primary leptomeningeal melanoma in a child is presented. The patient was studied with multiple neuroradiological methods, however computed tomography (CT) provided the most important information. The CT findings with leptomeningeal tumor, although not completely specific, do suggest the diagnosis, thus providing important information to explain the acute onset of symptoms in a previously healthy child. This case also differs from previously reported cases in terms of the type of hydrocephalus associated with the tumor.
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## BACKGROUND. Malignant melanoma (MM) is one of the least common types of childhood cancer, accounting for less than 1% of all pediatric malignancies. Neurocutaneous melanosis (NCM) is a rare phakomatosis consisting of congenital abnormal pigmentation of the skin and meninges. The meningeal lesio