In their excellent review of neuropsychiatric problems in Parkinson's disease (PD), 1 the authors made one small error but more importantly raised an interesting question about drug trials. Also, as they wrote their article, both melperone (personal communication) and pimavanserin, 2 subjected to ra
Neuropsychiatric symptoms in Parkinson's disease
β Scribed by Dag Aarsland; Laura Marsh; Anette Schrag
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 114 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Neuropsychiatric symptoms are common in Parkinson's disease, even at the earliest stages, and have important consequences for quality of life and daily functioning, are associated with increased carer burden and increased risk for nursing home admission. In addition to cognitive impairment, a wide range of neuropsychiatric symptoms have been reported. In this article, the epidemiology, clinical course, diagnosis, and management of some of the most common neuropsychiatric symptoms in PD are discussed: depression, anxiety, apathy, fatigue, and psychotic symptoms. Although much is known regarding the prevalence and course of these symptoms, the empirical evidence for how to manage these symptoms is limited at best. There is thus an urgent need for systematic studies for the pharmacological and nonβpharmacological management of these symptoms. Β© 2009 Movement Disorder Society
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