✦ LIBER ✦
Neuroprotective role of curcumin from Curcuma longa on ethanol-induced brain damage
✍ Scribed by V. Rajakrishnan; P. Viswanathan; K. N. Rajasekharan; Dr. Venugopal P. Menon
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 152 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0951-418X
No coin nor oath required. For personal study only.
✦ Synopsis
In the present study, curcumin from Curcuma longa was screened for neuroprotective activity using ethanol as a model of brain injury. Oral administration of curcumin to rats caused a significant reversal in lipid peroxidation, brain lipids and produced enhancement of glutathione, a non-enzymic antioxidant in ethanol intoxicated rats, revealing that the antioxidative and hypolipidaemic action of curcumin is responsible for its protective role against ethanol induced brain injury.