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Neuroprotective effects of the drug GVT (monosodium luminol) are mediated by the stabilization of Nrf2 in astrocytes

✍ Scribed by Pichili Vijaya Bhaskar Reddy; Gina Lungu; Xianghong Kuang; George Stoica; Paul K.Y. Wong


Book ID
116765457
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
530 KB
Volume
56
Category
Article
ISSN
0197-0186

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## Abstract The aim of the present study was to evaluate the neuroprotective effects of caffeine, an inhibitor of ataxia telangiectasia mutated (ATM) enzyme and an antagonist of adenosine receptors, in two models of apoptosis in cerebellar granule neurons (CGNs): the inhibition of mitochondrial com