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Neuroprotective effects of pramipexole against tunicamycin-induced cell death in PC12 cells

✍ Scribed by Hitoshi Nakayama; Jing Zhao; Amany EI-FAKhrany; Minoru Isosaki; Hiroyasu Satoh; Yoji Kyotani; Masanori Yoshizumi

Book ID
108940541
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
207 KB
Volume
36
Category
Article
ISSN
0305-1870

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## Abstract The prion protein peptide PrP106‐126 induces cell apoptosis through mechanisms involving production of intracellular reactive oxygen species. The present study investigated the effects of edaravone, a potent free radical scavenger in clinical use, on cell cytotoxicity induced by PrP106‐