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Neuroprotective Effects of Angiotensin II Type 1 Receptor (AT1-R) Blocker via Modulating AT1-R Signaling and Decreased Extracellular Glutamate Levels

✍ Scribed by Fujita, Tomoyoshi ;Hirooka, Kazuyuki ;Nakamura, Takehiro ;Itano, Toshifumi ;Nishiyama, Akira ;Nagai, Yukiko ;Shiraga, Fumio


Book ID
111907892
Publisher
Association for Research in Vision and Ophthalmology (ARVO)
Year
2012
Weight
839 KB
Volume
53
Category
Article
ISSN
1552-5783

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## Abstract Angiotensin II (Ang II) is a bioactive peptide of the renin–angiotensin system, acting not only as a vasoconstrictor but also as a growth promoter via angiotensin II type 1 receptor (AT1R) in some cancer. In this study, we examined the mechanisms by which Ang II affected the cell prolif

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