Neuroprotective effect of treatment with human albumin in permanent focal cerebral ischemia: histopathology and cortical perfusion studies

Neuroprotective effects of prostaglandin

Neuroprotective effects of prostaglandin A1 in rat models of permanent focal cerebral ischemia are associated with nuclear factor-κB inhibition and peroxisome proliferator-activated receptor-γ up-regulation

✍ Hui-Ling Zhang; Zhen-Lun Gu; Sean I. Savitz; Feng Han; Kohji Fukunaga; Zheng-Hon 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 822 KB

## Abstract We have previously reported that prostaglandin A~1~ (PGA~1~) reduces infarct size in rodent models of focal ischemia. This study seeks to elucidate the possible molecular mechanisms underlying PGA~1~'s neuroprotective effects against ischemic injury. Rats were subjected to permanent mid