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Neuroprotective effect of rasagiline, a monoamine oxidase-B inhibitor, on spontaneous cell degeneration in a rat model

โœ Scribed by S. Eliash; N. Shteter; R. Eilam

Publisher
Springer
Year
2005
Tongue
English
Weight
793 KB
Volume
112
Category
Article
ISSN
1435-1463

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Rasagiline (N-propargyl-1R-aminoindan) is a novel, potent, selective, and irreversible inhibitor of monoamine oxidase B (MAO-B), currently in Phase III trials for the treatment of Parkinson disease (PD). Rasagiline was shown to have neuroprotective properties in various in vitro and in vivo models i