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Neuroprotective effect of nitric oxide against NMDA-induced neurotoxicity in the rat retina is associated with tyrosine hydroxylase expression

✍ Scribed by Yasushi Kitaoka; Toshio Kumai; Kazuyuki Isenoumi; Yuka Kitaoka; Masamitsu Motoki; Shinichi Kobayashi; Satoki Ueno

Book ID: 113999455
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 746 KB
Volume: 977
Category: Article
ISSN: 0006-8993
DOI: 10.1016/s0006-8993(03)02696-9

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## Abstract Excitotoxicity and cell death induced by glutamate are involved in many neurodegenerative disorders. We have previously demonstrated that excitotoxicity induced by millimolar concentrations of glutamate in hippocampal slices involves apoptotic features and glutamate‐induced glutamate re